Mar 25 2010
由于由伊利诺伊大学研究人员团队开发的灵活的电子技术，与宾夕法尼亚大学医学院和西北大学合作，因此心律不齐的心很快就会再次及时击败，这要归功于最小的手术入侵。这些生物相容性的硅设备可以标志着新一波的手术电子设备的开始。
联合副作用约翰·罗杰斯（John Rogers），李·J·弗洛里（Lee J.欧洲杯足球竞彩欧洲杯线上买球
Several treatments are available for hearts that dance to their own tempo, ranging from pacemaker implants to cardiac ablation therapy, a process that selectively targets and destroys clusters of arrhythmic cells. Current techniques require multiple electrodes placed on the tissue in a time-consuming, point-by-point process to construct a patchwork cardiac map. In addition, the difficulty of connecting rigid, flat sensors to soft, curved tissue impedes the electrodes' ability to monitor and stimulate the heart.
Rogers and his team have built a flexible sensor array that can wrap around the heart to map large areas of tissue at once. The array contains 2,016 silicon nanomembrane transistors, each monitoring electricity coursing through a beating heart.
The Pennsylvania team demonstrated the transistor array on the beating hearts of live pigs, a common model for human hearts. They witnessed a high-resolution, real-time display of the pigs' pulsing cardiac tissues - something never before possible.
"We believe that this technology may herald a new generation of devices for localizing and treating abnormal heart rhythms," said co-sernior author Brian Litt, of the University of Pennsylvania.
“这使我们能够将硅电子设备的全部功率直接应用于组织，”罗杰斯（Rogers）在柔性，可拉伸电子产品领域的著名研究人员说。他说，作为可以直接与身体组织直接集成的第一类灵活电子产品，“这些方法可能有可能重新定义高级手术设备，植入物，假肢等的设计策略。”
生物相容性的电路 - 第一批被浸入人体咸液中的不受干扰的电路 - 代表了罗杰斯小组对七年的灵活电子研究的高潮。研究人员从Ultrathin，单晶硅在柔性或弹性基板上建造电路，例如塑料或橡胶。硅层的纳米薄度使得可以弯曲并折叠正常刚性半导体。
"If you can create a circuit that's compliant and bendable, you can integrate it very effectively with soft surfaces in the body," such as the irregular, constantly moving curves of the heart, Rogers said.
由Younggang Huang领导的西北大学的理论力学小组的合作提供了对设计的重要见解。
心脏传感器的拼布网格自行粘附在心脏的潮湿表面上，不需要探针或粘合剂，并且很容易抬起。数百个传感器的数组使心脏外科医生对心脏的电活动进行了更完整的了解，因此他们可以快速找到并修复任何短路。实际上，心脏设备具有用于非放置应用的任何类别的柔性电子设备的最高晶体管分辨率。
The team's next step is to adapt the technology for use with non-invasive catheter procedures, Rogers said. The U. of I. and Pennsylvania teams also are exploring applications for the arrays in neuroscience, applying grids to brain surfaces to study conditions of unusual electrical activity, such as epilepsy.
罗杰斯说：“它设定了一种新的设计范式，用于将电子设备与人体接口，并在人类健康中进行了许多可能的应用。”
Source:http://www.uillinois.edu