实验室可以访问先进的分析样品制备,纯化和分离溶液,以促进对类固醇激素和滥用药物的高分辨率分析。Thermo Fisher Scientific在3月17日至21日在费城宾夕法尼亚州会议中心举行的2019年匹兹堡会议与博览会(Pittcon 2019)期间展示了其新解决方案(Pittcon 2019)。
“As purification, preparation and separation are essential steps in every analytical workflow, scientists across the life sciences spectrum are demanding improvements across each step and higher levels of confidence in any data produced,”Thermo Fisher Scientific,色谱柱和消耗品副总裁兼总经理Molly Flick说。“Introducing our new workflow and column provides rapid access to high-quality data, revealing insights that will enable customers to make the world healthier, cleaner and safer.”
加速肽映射工作流程
The Thermo Scientific SMART Automation workflow is a comprehensive, easy-to-use liquid chromatography mass spectrometry (LC-MS) based analytical solution that overcomes the inefficiencies typically associated with protein characterization techniques by bringing together the existing Thermo Scientific SMART Digest Trypsin Kit with Magnetic Bulk Resin option with the Thermo Scientific KingFisher Duo Prime system with automated magnetic bead technology for flexible, fast and reproducible peptide mapping. The combination of these solutions into the SMART Automation workflow enables pharmaceutical, biopharma or drug manufacturing laboratories to achieve trypsin digestion in one hour with high levels of recovery, sensitivity and data quality in a format that is compatible with automation.
“必须分析生物治疗学以确保其安全性和功效,但是传统的肽映射技术通常很缓慢且耗时。”乔纳森·骨(Jonathan Bones)说,NIBRT的表征和可比性实验室 - 美国国家生物处理研究与培训研究所。“借助智能自动化工作流程,现在可以使用可重现的方法来准备生物治疗剂进行分析,从而有助于加速映射表征和样品中多种蛋白质的确认。”
滥用药物和类固醇激素的快速,可再现的分离
Thermo Scientific Accucore Biphenyl LC Column provides robust and reliable separation of isomeric compounds by pharmaceutical, clinical research and forensic laboratories, such as drugs of abuse and steroid isomers, and is designed to avoid the challenges of unresolved peaks, long run times and insufficient lot-to-lot consistency traditionally introduced by C18 columns. The Accucore Biphenyl LC column can support the optimization of critical parameters such as retention time stability and peak asymmetry while offering improved column life and compatibility with 100% aqueous conditions for the fast and sensitive separation of aromatic and moderately polar analytes from a variety of sample matrices.
For more information on Thermo Fisher’s solutions showcased at Pittcon 2019, please visitwww.thermofisher.com/pittcon。
Source:http://www.thermofisher.com/