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Exploration of a Bio-Friendly and Coral-Friendly Polymeric UV Filter

科学家通过聚合大分子的聚合可以防止紫外线辐射,但太大而无法渗透到人类的皮肤,珊瑚和藻类,从而为珊瑚礁友好的防晒霜创建了原型。

这是一个图形摘要,描绘了新的珊瑚友好的防晒霜及其特性。图片来源:Zeng等。

在阻断小鼠晒伤时,聚合物紫外线过滤器比当前的防晒霜更有效。该研究于3月1日发布英石,2023年,在日记中细胞报告物理科学欧洲杯线上买球s

This is an initial exploration of a new strategy to design bio-friendly and coral-friendly polymeric UV filters. We hope this leads to the next generation of sunscreens

Lei Tao, Study Senior Author and Chemist, Tsinghua University

在2010年访问了大堡礁之后,陶被激励调查环保的防晒霜。

I was blown away by the beautiful coral, and ever since I learnt that sunscreen is one of the causes of coral bleaching, I kept thinking about ways to develop a coral-friendly sunscreen.

Lei Tao, Study Senior Author and Chemist, Tsinghua University

Tao’s group started by using a chemical reaction to generate random ring-shaped molecules with structures similar to avobenzone, an existing UV filter. Then, using a second chemical reaction, they linked these ring-shaped molecules together in various combinations, yielding a set of candidate polymers to choose from. The scientists selected the best candidate by contrasting the SPF value of the polymers and their ability to absorb UV radiation.

当评估获胜的聚合物预防紫外线诱导的小鼠皮肤燃烧的能力时,科学家发现它显然优于羟赞酮,avobenzone和两种商业防晒霜。值得注意的是,小鼠没有通过皮肤吸收聚合物,也没有炎症或其他皮肤损伤。

聚合物紫外线过滤器还对珊瑚和藻类有希望,这两组有生物,这些生物会受到目前市场上的化学防晒霜的影响。

当研究人员在少量聚合物存在下种植小球藻时,不太可能受到影响,两种常见类型的珊瑚也不太可能受到影响。这些相同的珊瑚在暴露于氧苯甲酮中分别进行了6和20天,因此死亡并死亡。

The UV filter does not biodegrade given the structure of its chemical backbone, but the investigators claim that this is only the first step toward developing the next generation of environmentally safe UV filters.

我们对其他非随机聚合方法有一些想法,这些方法可以与我们在本研究中开发的化学群相结合,以创建环保且易于生物降解的紫外线过滤器。同时,我们将尝试与公司合作测试当前的聚合物,并查看是否可以在防晒霜中使用

Lei Tao, Study Senior Author and Chemist, Tsinghua University

期刊参考

Zeng,Y。,et al。(2023)通过Biginelli反应进行体内紫外线保护,对珊瑚友好和非透明聚合物紫外线过滤器。细胞报告物理科学欧洲杯线上买球doi.org/10.1016/j.xcrp.2023.101308

Source:https://www.cell.com/

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